Description
Reversible inhibitor of JNK1, 2, and 3 (IC50 = 0.11 µM); is cell-permeable and inhibits c-Jun phosphorylation in cells; blocks the expression of COX-2 and TNF-α in monocytes and IL-10, TNF-α, and IFN-γ in T-cells; prevents apoptosis in B-cells; inhibits autophagy in HeLa cells